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和厚樸酚

分析標準品,HPLC≥98%

Honokiol

CAS號：35354-74-6

分子式：C18H18O2

分子量：266.33

MDL：MFCD00016674

產品介紹

熔點：87.5℃

沸點：400.1℃ at 760 mmHg

外觀：棕褐色至白色精細粉末，單體為無色鱗片狀晶體

溶解性：可溶于一般的有機溶劑，易溶于苯，乙mi，氯仿，乙醇等，難溶于水。

儲存條件：2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(39篇)

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34. [IF=4.8] Haitao Li et al."Honokiol relieves hippocampal neuronal damage in Alzheimer's disease by activating the SIRT3‐mediated mitochondrial autophagy."CNS Neuroscience & Therapeutics.2024 Aug; 30(8): e14878

33. [IF=8.2] Yulong Wei et al."New insight into molecular mechanisms of different polyphenols affecting Sirtuin 3 deacetylation activity."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;:132026

32. [IF=3] Xiaoshuang He et al."Affinity character analysis of magnolol and honokiol based on stepwise frontal analysis coupled with cell membrane chromatography."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2023 Sep;1229:12

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29. [IF=2.866] Sun, Guang-wei et al."Honokiol Reduces Mitochondrial Dysfunction and Inhibits Apoptosis of Nerve Cells in Rats with Traumatic Brain Injury by Activating the Mitochondrial Unfolded Protein Response."JOURNAL OF MOLECULAR NEUROSCIENCE.2022 Dec;:1-9

28. [IF=3.251] Kanglei Zhang et al."Honokiol Antagonizes Cadmium-Induced Nephrotoxicity in Quail by Alleviating Autophagy Dysfunction, Apoptosis and Mitochondrial UPR Inhibition with Its Antioxidant Properties."Life-Basel.2022 Oct;12(10):1574

27. [IF=11.467] Xinmian Chen et al."Local delivery of gambogic acid to improve anti-tumor immunity against oral squamous cell carcinoma."JOURNAL OF CONTROLLED RELEASE.2022 Nov;351:381

26. [IF=4.927] Wenguang Jing et al."Application of Multiple-Source Data Fusion for the Discrimination of Two Botanical Origins of Magnolia Officinalis Cortex Based on E-Nose Measurements, E-Tongue Measurements, and Chemical Analysis."MOLECULES.2022 Jan;27(12):3892

25. [IF=3.373] Kewei Zhang et al."Discrimination between raw and ginger juice processed Magnoliae officinalis cortex based on HPLC and Heracles NEO ultra-fast gas phase electronic nose."Phytochemical Analysis. 2022 Mar 22

24. [IF=1.719] Xiaoying Zhu et al."Honokiol suppresses TNF-α-induced migration and matrix metalloproteinase expression by blocking NF-κB activation via the ERK signaling pathway in rat aortic smooth muscle cells."Acta Histochem. 2014 May;116:588

23. [IF=1.902] Junjun Wang et al."The pharmacokinetics and tissue distribution of curcumin and its metabolites in mice."Biomed Chromatogr. 2018 Sep;32(9):e4267

22. [IF=2.939] Fan  Shuli et al."Honokiol Inhibits Tumor Necrosis Factor-α-Stimulated Rat Aortic Smooth Muscle Cell Proliferation via Caspase- and Mitochondrial-Dependent Apoptosis."Inflammation. 2014 Feb;37(1):17-26

21. [IF=3.205] Dong-Dong Hu et al."Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan."J Chromatogr B. 2015 Sep;1000:136

20. [IF=5.418] Qiu  Ling et al."Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model."Exp Mol Med. 2015 Jul;47(7):e171-e171

19. [IF=5.81] Zhang  Xianhua et al."Pharmacokinetic Study of 7 Compounds Following Oral Administration of Fructus Aurantii to Depressive Rats."Front Pharmacol. 2018 Mar;0:131

18.  Qiu, Ling, et al. "Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model." Experimental & molecular medicine 47.7 (2015): e171-e171.

17.  Zhang X, Han L, Liu J, et al. Pharmacokinetic Study of 7 Compounds Following Oral Administration of Fructus Aurantii to Depressive Rats. Frontiers in Pharmacology. 2018 ;9:131. DOI: 10.3389/fphar.2018.00131. PMID: 29556193; PMCID: PMC5845165.

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1.  唐蘭如 陳一楨 張文娟 王俏 劉紅 陳勇.Box-Behnken Design-響應面優化法優化PEG化和厚樸酚長循環納米脂質體處方[J].湖北大學學報(自然科學版) 2018 40(04):418-423.

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