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白藜蘆醇

分析標(biāo)準(zhǔn)品,HPLC≥98%

Resveratrol

CAS號(hào)：501-36-0

分子式：C14H12O3

分子量：228.24

MDL：MFCD00133799

別名：白黎蘆醇

產(chǎn)品介紹

 Resveratrol (trans-Resveratrol; SRT501) 是一種天然多酚，具有抗氧化，抗炎，保護(hù)心臟和抗癌的特性。 它的靶點(diǎn)廣泛，如 mTOR、JAK、β-amyloid、Adenylyl cyclase、IKKβ、DNA polymerase。Resveratrol 也是一種特異性的 SIRT1 活化劑。Resveratrol 是有效的孕烷 X 受體 (PXR) 抑制劑。Resveratrol 是一種 Nrf2 激活劑，在小鼠模型中可以改善衰老相關(guān)的進(jìn)行性腎損傷。Resveratrol 作用于內(nèi)皮細(xì)胞促進(jìn) NO 產(chǎn)生。

熔點(diǎn)：253-255℃

沸點(diǎn)：449.1℃ at 760 mmHg

外觀：無色針狀結(jié)晶

溶解性：DMSO:100mg/mL(438.14mM;Needultrasonic)

Ethanol:50mg/mL(219.07mM;Needultrasonic)

儲(chǔ)存條件：-20℃

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(187篇)

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158. [IF=4] Menghan Wang et al."The interaction between resveratrol and catalase was studied by multispectral method and molecular docking simulation."JOURNAL OF MOLECULAR STRUCTURE.2024 Aug;:139720

157. [IF=4] Jie Gao et al."Punicalagin prevents the bone loss of diabetic mice induced by high-fat diet via the metabolism of gut microbiota."eFood.2024 Aug;5(5):e186

156. [IF=4.2] Liyan Liu et al."Unveiling the Catalytic Roles of DsBBS1 and DsBBS2 in the Bibenzyl Biosynthesis of Dendrobium sinense."MOLECULES.2024 Jan;29(15):3682

155. [IF=11] Mengxue Fang et al."Fabrication of resveratrol-loaded soy peptide nanogels with transglutaminase and in vitro gastrointestinal delivery and cholesterol-lowering effect."FOOD HYDROCOLLOIDS.2024 Dec;157:110437

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153. [IF=4.2] Decheng Meng et al."Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1α pathway."EUROPEAN JOURNAL OF PHARMACOLOGY.2024 Aug;977:176737

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133. [IF=8.8] Mi Yan et al."Hydroxyl group-induced enhancement of antioxidant activity of resveratrol over pterostilbene by binding to lactoferrin."FOOD CHEMISTRY.2024 May;441:138356

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131. [IF=6] Manzhu Liang et al."Mitigation mechanism of resveratrol on thermally induced trans-α-linolenic acid of trilinolenin."LWT-FOOD SCIENCE AND TECHNOLOGY.2023 Nov;:115508

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129. [IF=4.6] Qianchao Zhang et al."Modification of the 4-Hydroxyphenylacetate-3-hydroxylase Substrate Pocket to Increase Activity towards Resveratrol."MOLECULES.2023 Jan;28(14):5602

128. [IF=2.6] Zhu Tong et al."γ-Aminobutyric acid (GABA) mediated stilbene biosynthesis and alleviated oxidative stress induced by UV-C radiation during peanuts (Arachis hypogaea L.) germination."ACTA PHYSIOLOGIAE PLANTARUM.2023 Aug;45(8):1-14

127. [IF=4.5] Pengju Wang et al."Resveratrol protects against deoxynivalenol-induced ferroptosis in HepG2 cells."TOXICOLOGY.2023 Aug;494:153589

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123. [IF=6.51] Xiaoshun Jia et al."Use of surfactant-based amorphous solid dispersions for BDDCS class II drugs to enhance oral bioavailability: A case report of resveratrol."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Jun;641:123059

122. [IF=7.425] Xinlong Cheng et al."Cabernet sauvignon dry red wine ameliorates atherosclerosis in mice by regulating inflammation and endothelial function, activating AMPK phosphorylation, and modulating gut microbiota."FOOD RESEARCH INTERNATIONAL.2023 Jul;169:112942

121. [IF=4.803] Jie Liu et al."Dihydrotrichodimerol Purified from the Marine Fungus Acremonium citrinum Prevents NAFLD by Targeting PPARα."JOURNAL OF NATURAL PRODUCTS.2023;XXXX(XXX):XXX-XXX

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118. [IF=3.094] Li, Yayong et al."Nano-Resveratrol Liposome: Physicochemical Stability, In Vitro Release, and Cytotoxicity."APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY.2023 Feb;:1-16

117. [IF=4.927] Wenling Fan et al."Preparation of Solid Dispersion of Polygonum Cuspidatum Extract by Hot Melt Extrusion to Enhance Oral Bioavailability of Resveratrol."MOLECULES.2023 Jan;28(2):737

116. [IF=6.51] Jiawei Han et al."Mechanistic insight into gel formation of co-amorphous resveratrol and piperine during dissolution process."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Mar;634:122644

115. [IF=9.043] Lingbo Wang et al."Resveratrol Increases Sensitivity of Clinical Colistin-Resistant Pseudomonas aeruginosa to Colistin In Vitro and In Vivo | Microbiology Spectrum."Microbiology Spectrum.2022 Dec;:

114. [IF=6.269] Mengyu Cai et al."Nutritional supplements formulated to prevent cognitive impairment in animals."Current Research in Food Science.2022 Jan;5:2294

113. [IF=6.317] Xinlin Chen et al."Efficient discovery of potent α-glucosidase inhibitors from Paeoniae lactiflora using enzyme–MOF nanocomposites and competitive indicators."Food & Function.2022 Nov;:

112. [IF=6.656] Chong Chen et al."Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling."PHYTOMEDICINE.2022 Nov;:154546

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109. [IF=4.631] Dan-Dan Wang et al."AMPK/SIRT1 Deficiency Drives Adjuvant-Induced Arthritis in Rats by Promoting Glycolysis-Mediated Monocytes Inflammatory Polarization."Journal of Inflammation Research.2022; 15: 4663–4675

108. [IF=6.317] Jia-Ping Ke et al."Two new catechins from Zijuan green tea enhance the fitness and lifespan of Caenorhabditis elegans via insulin-like signaling pathways."Food & Function.2022 Aug;:

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105. [IF=7.425] Xiaoge Zhang et al."Pea protein based nanocarriers for lipophilic polyphenols: Spectroscopic analysis, characterization, chemical stability, antioxidant and molecular docking."FOOD RESEARCH INTERNATIONAL.2022 Oct;160:111713

104. [IF=9.231] Yuan Pan et al."Untargeted metabolomic analysis of Chinese red wines for geographical origin traceability by UPLC-QTOF-MS coupled with chemometrics."FOOD CHEMISTRY.2022 Nov;394:133473

103. [IF=6.208] Yan Chen et al."Characterization of the Key Bibenzyl Synthase in Dendrobium sinense."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(12):6780

102. [IF=6.317] Xiangyuan Meng et al."Protective effects of apple polyphenols on bone loss in mice with high fat diet-induced obesity."Food & Function.2022 Jun;:

101. [IF=5.82] Mingfang Tao et al."Vitexin and Isovitexin Act Through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans."MOLECULAR NUTRITION & FOOD RESEARCH. 2022 Apr 12

100. [IF=3.373] Yiyuan Luo et al."Quality evaluation of Tetrastigma hemsleyanum different parts based on quantitative analysis of 42 bioactive constituents combined with multivariate statistical analysis."PHYTOCHEMICAL ANALYSIS. 2022 Apr 05

99. [IF=4.411] Yuan Ma et al."Reflux Extraction Optimization and Antioxidant Activity of Phenolic Compounds from Pleioblastus amarus (Keng) Shell."Molecules. 2022 Jan;27(2):362

98. [IF=4.451] Suwen Liu et al."Castanea mollissima shell polyphenols regulate JAK2 and PPARγ expression to suppress inflammation and lipid accumulation by inhibiting M1 macrophages polarization."J Funct Foods. 2022 May;92:105046

97. [IF=9.147] Xiaoge Zhang et al.Study on simultaneous binding of resveratrol and curcumin to β-lactoglobulin: Multi-spectroscopic, molecular docking and molecular dynamics simulation approaches.Food Hydrocolloid. 2022 Mar;124:107331

96. [IF=2.081] Yu-An Hsu et al."Anti-Inflammatory Effects of Resveratrol on Human Retinal Pigment Cells and a Myopia Animal Model."Curr Issues Mol Biol. 2021 Sep;43(2):716-727

95. [IF=2.082] Qin Guo et al."Synergistic inhibition effects of tea polyphenols as adjuvant of oxytetracycline on Vibrio parahaemolyticus and enhancement of Vibriosis resistance of Exopalaemon carinicauda."Aquac Res. 2021 Aug;52(8):3900-3910

94. [IF=2.354] Zhu  Tong et al."Light radiation promoted stilbene accumulation in peanut sprouts: a response of the reestablishment of oxidant-antioxidant homeostasis."Acta Physiol Plant. 2021 Oct;43(10):1-14

93. [IF=3.205] Jie Tang et al."Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."J Chromatogr B. 2021 Aug;1179:122827

92. [IF=3.571] Suwen Liu et al."Lonicera caerulea Berry Polyphenols Activate SIRT1, Enhancing Inhibition of Raw264.7 Macrophage Foam Cell Formation and Promoting Cholesterol Efflux."J Agr Food Chem. 2019;67(25):7157–7166

91. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328

90. [IF=3.943] Si-wei Wang et al."Hesperetin, a SIRT1 activator, inhibits hepatic inflammation via AMPK/CREB pathway."Int Immunopharmacol. 2020 Dec;89:107036

89. [IF=4.192] Suwen Liu et al."Cerasus humilis Cherry Polyphenol Reduces High-Fat Diet-Induced Obesity in C57BL/6 Mice by Mitigating Fat Deposition, Inflammation, and Oxidation."J Agr Food Chem. 2020;68(15):4424–4436

88. [IF=4.36] Li Lin et al."Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism."J Ethnopharmacol. 2020 Apr;252:112577

87. [IF=5.279] Tong Zhu et al."Effects of White LED Light and UV-C Radiation on Stilbene Biosynthesis and Phytochemicals Accumulation Identified by UHPLC–MS/MS during Peanut (Arachis hypogaea L.) Germination."J Agr Food Chem. 2020;68(21):5900–5909

86. [IF=5.279] Xintong Tan et al."Resveratrol Prevents Acrylamide-Induced Mitochondrial Dysfunction and Inflammatory Responses via Targeting Circadian Regulator Bmal1 and Cry1 in Hepatocytes."J Agr Food Chem. 2019;67(31):8510–8519

85. [IF=5.396] Meigui Huang et al."Liposome co-encapsulation as a strategy for the delivery of curcumin and resveratrol."Food Funct. 2019 Oct;10(10):6447-6458

84. [IF=5.833] Zhou  Zhidu et al."Ultra-sensitive amperometric determination of quercetin by using a glassy carbon electrode modified with a nanocomposite prepared from aminated graphene quantum dots, thiolated β-cyclodextrin and gold nanoparticles."Microchim Acta. 2020

83. [IF=6.306] Yunke Huang et al."Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox."Food Chem. 2021 Jun;:130323

82. [IF=6.583] Xing Zhang et al."Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways."Brit J Pharmacol. 2019 Dec;176(24):4745-4759

81. [IF=7.514] Bowei Zhang et al."Intestinal pharmacokinetics of resveratrol and regulatory effects of resveratrol metabolites on gut barrier and gut microbiota."Food Chem. 2021 Sep;357:129532

80. [IF=2.391] Sun  Hui et al."Ultrasound-assisted extraction of resveratrol from grape leaves and its purification on mesoporous carbon."Food Sci Biotechnol. 2018 Oct;27(5):1353-1359

79. [IF=2.478] De-Quan Zhang et al."Resveratrol Regulates Activated Hepatic Stellate Cells by Modulating NF‐κB and the PI3K/Akt Signaling Pathway."J Food Sci. 2016 Jan;81(1):H240-H245

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